Posted on February 28, 2009
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CONCLUSION: To our knowledge, no report investigating the skin findings among thyroid diseases exists in literature. We believe this study would provide data for further studies.
PMID: 19327604 [PubMed - in process] (Source: European Journal of Internal Medicine)
Posted on February 28, 2009
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Authors: Pfeifer SM, Kives S
Polycystic ovary syndrome (PCOS) is now recognized as a heterogeneous disorder that results in overproduction of androgens, primarily from the ovary, leading to anovulation and hirsutism and is associated with insulin resistance. Long-term sequellae of PCOS include higher risk for diabetes, obesity, metabolic syndrome, endometrial hyperplasia, and anovulatory infertility. Symptoms in the adolescent include oligomenorrhea, hirsutism, acne, and weight gain. Insulin resistance, impaired glucose tolerance, and diabetes have also been demonstrated in adolescents who have PCOS. Treatment should be instituted early to decrease symptoms and long term sequellae of PCOS. Weight loss, oral contraceptives, and antiandrogens are effective in treating the symptoms of thi...
Posted on February 28, 2009
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There was much that was wonderful about the advice from Dr. Alfred T. Lane, especially the concept of “touching” patients with acne (“Treatments for Acne, Beginning With Touch,” October 2008, p. 34). (Source: Pediatric News)
Posted on February 28, 2009
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Authors: Veillette A, Rhee I, Souza CM, Davidson D
The proline-, glutamic acid-, serine- and threonine-rich (PEST) family of protein tyrosine phosphatases (PTPs) includes proline-enriched phosphatase (PEP)/lymphoid tyrosine phosphatase (LYP), PTP-PEST, and PTP-hematopoietic stem cell fraction (HSCF). PEP/LYP is a potent inhibitor of T-cell activation, principally by suppressing the activity of Src family protein tyrosine kinases (PTKs). This function seems to be dependent, at least in part, on the ability of PEP to bind C-terminal Src kinase (Csk), a PTK also involved in inactivating Src kinases. Interestingly, a polymorphism of LYP in humans (R620W) is a significant risk factor for autoimmune diseases including type 1 diabetes, rheumatoid arthritis, and lupus. The R620W mutation may b...
Posted on February 28, 2009
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Authors: Laubscher T, Regier L, Jin M, Jensen B
PMID: 19282536 [PubMed - in process] (Source: Canadian Family Physician Medecin de Famille Canadien)
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