New Acne Guidelines Stress Early, Aggressive Tx

Posted on May 31, 2009
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Since acne is a chronic disease capable of causing serious psychological and social problems, it warrants early, aggressive treatment and prolonged maintenance therapy, according to updated treatment guidelines. (Source: Pediatric News)

[Therapeutics] Clindamycin and benzoyl peroxide combined was more effective than either agent alone or placebo for acne vulgaris

Posted on May 28, 2009
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(Source: Evidence-Based Medicine)

Clinical and radiologic evolution of synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome: A single center study of a cohort of 71 subjects

Posted on May 27, 2009
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To assess the basic features and outcomes of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome.We identified all patients seen in our unit between 1990 and 2008 diagnosed according to the proposed inclusion criteria with SAPHO syndrome, who had a followup of at least 2 years.Seventy-one patients (48 women, 23 men) with SAPHO syndrome were identified. The median disease duration at the end of followup was 10 years (interquartile range [IQR] 7-15 years), and the median followup duration was 11 years (IQR 6-11.5 years). Six patients were diagnosed with Crohn's disease. Fourteen patients had never had cutaneous involvement, but 8 patients presented >1 skin manifestation. Nine patients (13%) presented a limited (6 months. A total of 4% of the patients were HLA-B27 positiv...

Increased interferon-γ, interleukin-12p40 and IL-8 production in Propionibacterium acnes-treated peripheral blood mononuclear cells from patient with acne vulgaris: Host response but not bacterial species is the determinant factor of the disease

Posted on May 27, 2009
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Conclusions: The inflammatory response of acne appears to be attributable to P. acnes-induced host immune response rather than P. acnes strains from normal skin or acne lesions. (Source: Journal of Dermatological Science)

 

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Increased interferon-γ, interleukin-12p40 and IL-8 production in Propionibacterium acnes-treated peripheral blood mononuclear cells from patient with acne vulgaris: Host response but not bacterial species is the determinant factor of the disease

Posted on May 27, 2009
Filed Under Acne | Leave a Comment

Conclusions: The inflammatory response of acne appears to be attributable to P. acnes-induced host immune response rather than P. acnes strains from normal skin or acne lesions. (Source: Journal of Dermatological Science) « go backkeep looking »