A mechanism-based classification of dermatologic reactions to biologic agents used in the treatment of cutaneous disease: Part 1.

Posted on July 31, 2009
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Authors: Bremmer M, Deng A, Gaspari AA Biologic therapies are an efficacious new method of controlling a number of chronic conditions. Data regarding these medications continues to emerge, giving clinicians a greater understanding of their side effects profiles. The biologic agents used in dermatology, particularly the tumor necrosis factor-alpha inhibitors, have a number of varied dermatologic side effects. In this two-part article, we perform a review of literature regarding the cutaneous side effects of infliximab, etanercept, adalimumab, rituximab, efalizumab, and alefacept. In Part 1, we will discuss cutaneous infections, malignancy, rebound phenomenon, eczema, atopic dermatitis, lichenoid reactions, granulomatous disease, pruritus, acne, and progressive multifocal leukoencephalop...

Congenital adrenal hyperplasia

Posted on July 31, 2009
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Abstract: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder of adrenal steroid biosynthesis affecting 1/10,000 to 1/15,000 live births. The most common form is 21-hydroxylase deficiency due to mutations in the CYP21A2 gene. CAH classically presents at birth with ambiguous genitalia in an affected female. Salt loss, the only sign in an affected newborn male, affects the majority and can be life-threatening. An adolescent female with CAH has a syndrome of hirsutism, acne and irregular periods. Treatment aims to replace adequate amounts of glucocorticoid and mineralocorticoid hormones but avoid side effects such as growth suppression. Serum 17OH-progesterone is increased in CAH due to 21-hydroxylase deficiency and is a useful marker to monitor treatment. Surgery for ambi...

Skin tears

Posted on July 30, 2009
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Preventing and treating a common condition among elderly patients Toronto - Clinicians need to inform patients of simple preventative steps they can take to avoid skin tears from occurring on various sites of the body, an expert says. Speaking in Toronto at the World Union of Wound Healing

Publication: Dermatology Times

Skin tears

Posted on July 30, 2009
Filed Under Acne, Uncategorized | Leave a Comment

Preventing and treating a common condition among elderly patients Toronto - Clinicians need to inform patients of simple preventative steps they can take to avoid skin tears from occurring on various sites of the body, an expert says. Speaking in Toronto at the World Union of Wound Healing

Publication: Dermatology Times

SKIN YOU’LL FALL FOR

Posted on July 30, 2009
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No matter your skin type, we have the game plan for clear, beautiful skin. Here comes fall weather-but be prepared for sudden temperature changes during this transitional season. It's important to practice preventive and corrective skin care (cleanse, exfoliate and moisturize regularly), apply a

Publication: American Cheerleader keep looking »